One of the most important female reproductive hormones in the human body is oestrogen. During the early part of the menstrual cycle, it is present in high concentrations in women. Excess oestrogen, whether from within or outside the body, can lower your risk of a variety of ailments, including heart disease and cancer.
The term "internal estrogens" refers to estrogens produced by the human body (internal). External estrogens can come from artificial sources (xenoestrogens) or natural sources (estrogens from plants) (phytoestrogens). Estrone (E1), estradiol (E2), and estriol (E3) are three naturally occurring estrogens in women (E3).
Estrogen is involved in the menstrual cycle and the reproductive system in women. It is critical for male sexual function and can have an impact on general health and development. Females have greater oestrogen levels than males, who have more testosterone, the major male sex hormone.
Estrogen HRT causes the testes to atrophy (shrink) over time, reducing their ability to produce testosterone. Most trans women can reduce their antiandrogen dose over time, which is a good idea. The higher the oestrogen dosage, the more testosterone synthesis is likely to be suppressed.