Transmission of sexually transmitted infection (STI) pathogens from an infected donor to the receiver of a semen donation in assisted conception can lead to not only acute infection, but also long-term reproductive difficulties or negative pregnancy outcomes, including infection of the offspring. Amplification controls should be used to check false-negative results caused by inhibitory compounds in the semen sample. After reviewing over 3,800 research, doctors at the University of Oxford created a comprehensive list.
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