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Gliomas are malignant tumors that originate in the glial cells of the central nervous system. Scientists classify three major types of glioma, with an estimated 10,000 to 12,400 new cases diagnosed each year in the United States alone. The most common type is glioblastoma multiforme (GBM), which accounts for about 85% of all diagnosed cases.
Approximately 90% of patients with GBM survive for 2 years or more following diagnosis due to widespread use of radiation and chemotherapy treatment strategies that are directed at a tumor's location and not its genetics or cell type. This type of treatment is often successful even when cancer-free margins were not successfully obtained by surgery during diagnosis and staging procedures.
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